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This Year’s Take on Metastatic Anal Cancer (2012)

September 19, 2012

Well-done round-up of where we are with metastatic SCAC.

http://www.isrn.com/journals/oncology/2012/756591/

He found Hainsworth’s study the “most encouraging.”

“The most encouraging results have been demonstrated in a phase II single arm study of paclitaxel, carboplatin, and continuous infusional 5FU in patients with advanced squamous carcinomas (
𝑛 = 6 0
) from multiple primary sites, given first or second line. Seven patients with SCC of the anus were included, of these four responded, two of whom had a complete response. The patients with a complete response then received consolidation radiotherapy to the primary tumour. The median duration of response in the anal subgroup was 26 months (range 10–63+) [14]. “

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